The exact causes of psychosis are not entirely clear, but factors such as genetics, environment, illness, and mental disorders can all play a potential role. This article explores some of the common causes that are associated with psychosis. 

Common Causes

Some of the most common causes associated with psychosis include:

Schizophrenia and other mental disordersPhysical illnessSubstance useTrauma

Genetic Causes of Psychosis

Some evidence suggests that genes can increase your risk of developing psychosis. If someone in your family has had a psychotic episode, you may have a slightly higher risk of experiencing one too.  It is important to note that while psychosis appears to have a genetic component, having a family member with a psychotic condition does not necessarily mean you will also develop the condition.

Mental Health Conditions

Psychosis is a symptom of a number of different mental health conditions. Some conditions that can cause episodes of psychosis include:

Bipolar Disorder

Bipolar disorder is a condition characterized by recurrent episodes of extremely high moods (mania) and extremely low moods (depression). Psychosis can occur when a person has this condition, but they tend to be more common during a manic episode. While the experience varies from one person to the next, psychotic symptoms that often occur in bipolar disorder include:

Disorganized thinking: People may have incoherent, confusing thoughts that make it difficult for them to function and interact normally. Grandiosity: Those with the condition can experience an inflated sense of self characterized by feelings of grandeur and the belief that the person is uniquely special or that they have special powers. Hallucinations: Individuals may see or hear things that are not really there.

Brief Psychotic Disorder

This involves a short-term occurrence of psychotic behavior. It often occurs as a result of a stressful event. A brief psychotic episode can last from one day to up to a month. 

Major Depressive Disorder With Psychotic Features

Sometimes referred to as psychotic depression, symptoms of psychosis may also sometimes occur in this type of major depressive disorder.  People with this condition have symptoms of depression such as sadness, irritability, and loss of interest. However, they also experience delusions, hallucinations, or both.

Schizophrenia

Psychosis is a hallmark symptom of schizophrenia, a serious mental health condition that causes disordered thoughts and behaviors. People who have this condition can experience positive symptoms (which means that they cause changes in behavior and thought) as well as negative symptoms (which are marked by people withdrawing from the world).  In order to be diagnosed with schizophrenia, a person must experience at least one psychotic episode. These episodes are marked by delusions, hallucinations, and disorganized speech as well as disorganized behavior and negative symptoms such as a lack of emotional expression.

Postpartum Psychosis

At its most severe, postpartum depression may lead to symptoms of psychosis, which is serious and requires hospitalization. Postpartum psychosis most commonly occurs within two weeks of giving birth. Research suggests that having bipolar disorder or schizoaffective disorder increases the risk of developing postpartum psychosis.

Schizoaffective Disorder

Schizoaffective disorder is a condition marked by symptoms of both psychosis and mood disruptions. Similar to schizophrenia, this condition causes people to experience problems in how they perceive reality. Along with hallucinations and delusions, they also experience problems with emotions, thinking, and social interactions.

Substance Use

Psychosis can also be caused by the use of recreational substances. In some instances, prescription medications can also trigger a psychotic episode, particularly if they are misused or a person overdoses.  When a person experiences psychosis as a result of taking a substance, it is known as substance/medication-induced psychotic disorder. Substances that might cause psychosis include:

Amphetamines Cannabis (marijuana) Cocaine Ketamine LSD MDMA (ecstasy) Methamphetamine Psilocybin (magic mushrooms)

People with a history of substance abuse are at an increased risk of developing psychosis. This may be due to the effects that drugs and alcohol have on the brain, or it may be that people with underlying mental health conditions are more likely to self-medicate with substances.

Trauma

Traumatic life events, such as abuse or violence, can also increase the risk for psychosis. Being exposed to the trauma of war or enduring the death of a loved one, for example, has been known to play a role in the emergence of psychosis. Some symptoms of psychosis, particularly hallucinations, can occur when a person has post-traumatic stress disorder (PTSD) following a traumatic experience. However, evidence also suggests that the association between trauma and psychosis is complex. Psychosis may occur as a part of PTSD as a result of having experienced a traumatic experience, but experiencing psychotic symptoms can also lead to trauma.

Medical Conditions and Injury

Damage to the brain from illness or injury can also cause psychosis. A number of different medical conditions can also cause episodes of psychosis. Some of these conditions include:

Alzheimer’s disease Brain tumors HIV/AIDS Hormone disorders Hypoglycemia Lewy body disease Lupus Lyme disease Malaria Multiple sclerosis Parkinson’s disease Stroke

A Word From Verywell

While the causes of psychosis are not completely understood, it is clear that there are many different factors that can play a role. If you or someone you know is experiencing symptoms of psychosis, it is important to seek professional help right away. There are effective treatments available that can help people recover. Consult your healthcare provider to learn more about your options and to determine why you are experiencing this symptom.