The relationship between these emotions—and their associated clinical conditions, anxiety disorders and mood disorders—is complex and somewhat idiosyncratic. For one person, anxiety can lead to avoidance and isolation. Isolation can result in a lack of opportunity for pleasurable experiences, which then leads to low mood. For others, the emotions may flow in the opposite direction. Feeling down may zap someone of the energy to do things they typically enjoy, and attempts to re-engage with the world after being out of practice may result in nervousness. Understanding the distinctions between the two emotions (anxiety vs. depression) and characterizing the severity of the problem can help you to determine how to feel better. While the biological underpinnings of these problems are similar, anxiety and depression are experienced differently. In this way, the two states might be considered two sides of the same coin. Anxiety and depression can occur sequentially (one in reaction to the other), or they can co-occur. When anxiety and mood problems reach the threshold for clinical diagnosis simultaneously, the specific diagnoses are considered comorbid conditions.

Mental Markers of Anxiety

People with anxiety may:

Worry about the immediate or long-term future Have uncontrollable, racing thoughts about something going wrong Avoid situations that could cause anxiety so that feelings and thoughts don’t become consuming Think about death, in the sense of fearing death due to the perceived danger of physical symptoms or anticipated dangerous outcomes

Depending on the nature of the anxiety, these mental markers can vary. For example, someone with generalized anxiety disorder (GAD) may worry about a variety of topics, events, or activities. A person with social anxiety disorder (SAD), on the other hand, is more apt to fear negative evaluation or rejection by others and to be apprehensive about meeting new people or other socially challenging situations. Obsessions are unrealistic thoughts or mental impulses (sometimes with a magical quality) that extend beyond everyday worries. They are the hallmark mental manifestation of anxiety in people with ​obsessive-compulsive disorder (OCD).

Mental Markers of Depression

People with depression may:

Be hopeless, assuming that nothing positive will happen in the future for themselves, for others, or for the worldBelieve it is not worth trying to think or feel differently, because of this hopelessnessFeel worthless, as if who they are or what they do is not valuableThink about death due to a persistent belief that life is not worth living or that the individual is a burden on others. In cases of moderate to severe depression, more specific suicidal thoughts can be present.

In major depressive disorder (MDD), these types of thoughts are persistent most of the day and more days than not for weeks on end. If a person vacillates between a very low and very high mood state, then a diagnosis of bipolar disorder may apply. For any variant of a mood disorder, the low mood state is likely to be characterized by the type of thinking described above. For more mental health resources, see our National Helpline Database.

Physical Signs of Anxiety

The physical state of anxiety can be conceptualized overall as that of heightened arousal. Specific characteristics include:

Difficulty concentrating due to state of agitation or racing thoughtsDifficulty falling or staying asleep due to racing thoughts or other physical symptomsDizzinessGastrointestinal distress (e.g., nausea, diarrhea, or constipation)Increased heart rate, blood pressure, sweatingMuscle tensionShortness of breath

Physical Signs of Depression

Depression is primarily characterized by changes in usual physical processes from baseline, such as:

Difficulty with concentration, focus, and memory due to ruminative thought processes or other physical symptomsLack of energyLoss of appetite or a significant increase in appetiteMoving or talking more slowly than usualPhysical achiness without causeSleeping much more or much less than is typical due to ruminative thought processes or low energy

To meet the diagnostic threshold of an anxiety disorder, however, symptoms must be persistent (often for several months) and impairing. To assess the severity of your symptoms:

Self-Help Approaches

If your symptoms are mild, tending to ebb and flow, or if you have had formal treatment previously and are concerned about relapse, self-help interventions can be a reasonable place to start. These approaches can include self-help books and phone apps that adapt evidence-based psychotherapies or offer a way to practice skills that target a symptom (such as mindfulness meditation for anger or anxiety).​

Psychotherapy

For depression and/or anxiety problems, there are several types of talk therapy. In structured psychotherapy, like cognitive behavioral therapy (CBT), the treatment approach for anxiety and depression can vary slightly. For both issues, CBT will teach you how to work with unhelpful thought traps. And, for either problem, CBT is likely to ask that you do more behaviorally. For anxiety, the goal is to minimize avoidant behavior and to help you disconfirm a feared consequence. For depression, the goal is to help you experience positive emotion, a surge in energy (even if briefly), or another type of pleasant interaction with the world. The theory is that activating behavior, even when—or especially when—your energy or mood is low, can result in some type of positive reward. In psychodynamic talk therapy, sessions for anxiety and depression may look more alike than different. You will be asked to speak freely about the past and the present in order to become aware of unconscious thoughts and conflicts underlying your symptoms. Do not despair if you think you are experiencing separate, co-occurring anxiety and mood symptoms. There is an overlap in effective psychotherapies for these problems.

Medications

A group of medications known as selective serotonin reuptake inhibitors (SSRIs) has been shown to be helpful for both anxiety and depression. Other medications that may be used depending on your symptoms include tricyclic antidepressants (TCAs), selective norepinephrine reuptake inhibitors (SNRIs), and anti-anxiety medications. You can also research local referrals via national organizations including:

The Anxiety and Depression Association of America The Association for Behavioral and Cognitive Therapies The Association for Contextual Behavioral Science The American Psychiatric Association             

Bear in mind that while effective treatment for anxiety or depression need not be a long-term commitment, it is likely to require regular, ongoing appointments at least in the short term (say, six to 12 months). Therefore, it is critical to find a professional you trust and with whom you feel comfortable speaking about your symptoms. It is equally important to make sure that you find a clinician that you can afford. Before making the commitment to ongoing care, you may want to meet with a couple of providers to get a feel for their therapeutic styles and their treatment recommendations. You can then use this information to determine which path forward feels best to you.